Respiratory Viruses and Torque Teno Virus in Adults with Acute Respiratory Infections

Objective: To define the molecular epidemiology of respiratory viral infections in adult patients. Methods: Nasal and throat swabs were collected from all adult patients with influenza-like illness (ILI), acute respiratory infection (ARI), or severe ARI (SARI) admitted to a tertiary hospital in Surakarta, Indonesia, between March 2010 and April 2011 and analyzed for 19 respiratory viruses and for torque teno virus (TTV) and human gyrovirus (HGyV). Results: Respiratory viruses were detected in 61.3% of the subjects, most of whom had ARI (90.8%, OR = 11.39), were hospitalized (96.9%, OR = 22.31), had asthma exacerbation (90.9%, OR = 8.67), and/or had pneumonia (80%, OR = 4.0). Human rhinovirus (HRV) A43 predominated. Influenza A H3N2, human metapneumovirus (HMPV) subtypes A1 and A2, the influenza B virus, human adenovirus B, and human coronavirus OC43 were also detected. All respiratory viruses were detected in the transition month between the rainy and dry seasons. No mixed respiratory virus infection was found. Coinfections of the influenza Received: June 23, 2014 Accepted after revision: October 18, 2014 Published online: February 10, 2015 Afiono Agung Prasetyo Department of Microbiology, Faculty of Medicine Sebelas Maret University Jl. Ir. Sutami No. 36A, Surakarta 57126 (Indonesia) E-Mail afie.agp.la @ gmail.com © 2015 S. Karger AG, Basel 0300–5526/15/0581–0057$39.50/0